MS-1020 is a JAK3 and STAT3 inhibitor. MS-1020 potently inhibits persistently-active STAT3 in a cell type-specific manner. MS-1020 selectively blocks constitutively-active JAK3 and consistently suppressed interleukin-2-induced JAK3/STAT5 signalling. References: Kim BH, Oh SR, Yin CH, Lee S, Kim EA, Kim MS, Sandoval C, Jayabose S, Bach EA, Lee HK, Baeg GH. MS-1020 is a novel small molecule that selectively inhibits JAK3 activity. Br J Haematol. 2010 Jan;148(1):132-43. doi: 10.1111/j.1365-2141.2009.07925.x. Epub 2009 Sep 29. PubMed PMID: 19793252; PubMed Central PMCID: PMC3034357.

纯度：≥98%

CAS：1255516-86-9