AZD-1386 is a transient receptor potential vanilloid 1'(TRPV1) antagonist. AZD1386 has been shown to increase oesophageal and skin heat pain thresholds. This drug class may have a potential for treatment of GERD. References: Quiding H, Jonzon B, Svensson O, Webster L, Reimfelt A, Karin A, Karlsten R, Segerdahl M. TRPV1 antagonistic analgesic effect: a randomized study of AZD1386 in pain after third molar extraction. Pain. 2013 Jun;154(6):808-12. doi: 10.1016/j.pain.2013.02.004. Epub 2013 Feb 19. PubMed PMID: 23541425.

纯度：≥98%

CAS：942937-80-6