NGB2904 is a potent and selective dopamine D3 receptor antagonist (Kis are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively). NGB2904 potently antagonizes quinpirole-stimulated mitogenesis (IC50 = 6.8 nM) References: Hussein N, Amawi H, Karthikeyan C, Hall FS, Mittal R, Trivedi P, Ashby CR Jr, Tiwari AK. The dopamine D(3) receptor antagonists PG01037, NGB2904, SB277011A, and U99194 reverse ABCG2 transporter-mediated drug resistance in cancer cell lines. Cancer Lett. 2017 Mar 18. pii: S0304-3835(17)30179-9. doi: 10.1016/j.canlet.2017.03.015. [Epub ahead of print] PubMed PMID: 28323029.

纯度：≥98%

CAS：189060-98-8