| CAS NO: | 32619-42-4 |
| 规格: | ≥98% |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| 250mg | 电议 |
| 500mg | 电议 |
| Molecular Weight (MW) | 540.51 |
|---|---|
| Formula | C25H32O13 |
| CAS No. | 32619-42-4 |
| Storage | -20℃ for 3 years in powder form |
| -80℃ for 2 years in solvent | |
| Solubility (In vitro) | DMSO: 100 mg/mL (185.0 mM) |
| Water: 100 mg/mL (185.0 mM) | |
| Ethanol: 100 mg/mL (185.0 mM) | |
| Solubility (In vivo) | PBS: 30mg/mL |
| Synonyms | Methyl (4S,5E,6S)-4-[2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl]-5-ethylidene-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4H-pyran-3-carboxylate |
| In Vitro | In vitro activity: In both J774A.1 cells and primary mouse macrophages, Oleuropein increases LPS-induced NO production. Oleuropein prevents oxidative myocardial injury induced by ischemia and reperfusion. In TF-1a; 786-O, T-47D, RPMI-7951, LoVo, and NL-Fib cells, Oleuropein inhibits cell proliferation and migration. |
|---|---|
| In Vivo | In swiss albino mice that spontaneously develop soft tissue sarcomas, Oleuropein (i.p. or p.o.) completely regresses tumors. In rats, Oleuropein (40 mg/kg, p.o.) protects from cardiac remodeling process after isoproterenol-induced myocardial infarction through inhibiting angiotensin-converting enzyme activity. |
| Animal model | Swiss albino mice that spontaneously develops soft tissue sarcomas |
| Formulation & Dosage | Dissolved in PBS; 50 μg/mouse; i.p. or p.o. administration |
| References | Life Sci. 1998;62(6):541-6; Biochem Biophys Res Commun. 2005 Sep 2;334(3):769-78. |
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