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Cyproheptadine HCl
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cyproheptadine HCl图片
CAS NO:969-33-5
规格:≥98%
包装与价格:
包装价格(元)
5g电议
10g电议
25g电议
50g电议

产品介绍
理化性质和储存条件
Molecular Weight (MW)323.86
FormulaC21H21N.HCl
CAS No.969-33-5
Storage-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)DMSO: 65 mg/mL (200.7 mM)
Water: <1 mg/mL
Ethanol: 20 mg/mL (61.8 mM)
SMILESCN1CC/C(CC1)=C2C3=CC=CC=C3C=CC4=CC=CC=C/24.Cl
SynonymsPeriactin; Eiproheptadine; Periactinol; Cyproheptadine Hydrochloride Sesquihydrate; Dronactin; Ciproheptadina; Peritol
实验参考方法
In Vitro

In vitro activity: Cyproheptadine is a serotonin and histamine antagonist as well as an antimuscarinic reagent. It is used to treat for postgastrectomy-dumping syndrome, pruritic dermatoses, migraine, anorexia, and pituitary-dependent Cushing's syndrome. The major urinary product of cyproheptadine is cyproheptadine glucuronide, a quaternary ammonium compound. Cyproheptadine has some side effects including sedation, drowsiness, hypotension, tachycardia and blood dyscrasias.

In Vivoa 5-HT2A receptor antagonist, cyproheptadine is found to reverse serotonin-enhanced ADP-induced platelet aggregation in vitro and ex vivo suggesting its antiplatelet and thromboprotective effects.
Animal model
Formulation & Dosage
References

J Anal Toxicol. 1998 Jan-Feb;22(1):72-4; PLoS One. 2014 Jan 23;9(1):e87026.