Niridazole can be used to treat schistosomiasis, the helmintic disease caused by certain flatworms (trematodes) from the genus Schistosoma (formerly Bilharzia), although it has central nervous system toxicity. Niridazole is rapidly concentrated in the parasite and inhibits oogenesis and spermatogenesis. The compound also inhibits the phosphofructokinase enzyme, leading to glycogen depletion and hepatic shift. It has also been studied as biodegradable inserts for local long-term treatment of periodontitis. References: Barat R, Srinatha A, Pandit JK, Ridhurkar D, Balasubramaniam J, Mittal N, Mishra DN. Niridazole biodegradable inserts for local long-term treatment of periodontitis: possible new life for an orphan drug. Drug Deliv. 2006 Sep-Oct;13(5):365-73. PubMed PMID: 16877312.

纯度：≥98%

CAS：61-57-4