NNC269100 is a somatostatin sst4 receptor agonist that exhibits > 100-fold selectivity over sst2 receptors (Kis are 6 and 621 nM for sst4 and sst2 receptors respectively). NNC269100 potently inhibits forskolin-induced cAMP accumulation (EC50 = 26 nM). References: Liu S, Crider AM, Tang C, Ho B, Ankersen M, Stidsen CE. 2-pyridylthioureas: novel nonpeptide somatostatin agonists with SST4 selectivity. Curr Pharm Des. 1999 Apr;5(4):255-63. Review. PubMed PMID: 10101224.

纯度：≥98%

CAS：199522-35-5