Hydroorotic acid, L-is a precursor to the biological pyrimidines, such as thymine, uracil, cytosine and hydroxymethylcytosine. When employed in large amounts D-dihydroorotic acid is an antimetabolite of L-dihydroorotic acid in pyrimidine utilization. It has also been found to inhibit the orotic acid utilization of those organisms which have a requirement for it in order to grow. In general it may be said to inhibit bacterial growth. References: Tiwari K, Kumar R, Dubey VK. Biochemical characterization of dihydroorotase of Leishmania donovani: Understanding pyrimidine metabolism through its inhibition. Biochimie. 2016 Dec;1345-53. doi: 10.1016/j.biochi.2016.09.009. Epub 2016 Sep 17. PubMed PMID: 27650727.

纯度：≥98%

CAS：5988-19-2