U0126-EtOH 是一种有效，非 ATP 竞争性的，选择性的 MEK1 和 MEK2 抑制剂，IC50 分别为 72 nM 和 58 nM。U0126-EtOH 是一种自噬 (autophagy) 和线粒体自噬 (mitophagy) 抑制剂。
| 中文别名 | U0126-EtOH;(2Z,3Z)-2,3-bis(amino((2-aminophenyl)thio)methylene)succinonitrile compound with ethanol (11) |
| 英文别名 | U0126-EtOH; U0126EtOH; U0126 EtOH, U0126, U-0126, U 0126 |
| CAS号 | 1173097-76-1 |
| SMILES | CCO.C1=CC=C(C(=C1)N)SC(=C(C#N)C(=C(N)SC2=CC=CC=C2N)C#N)N |
| Inchi | InChI=1S/C18H16N6S2.C2H6O/c19-9-11(17(23)25-15-7-3-1-5-13(15)21)12(10-20)18(24)26-16-8-4-2-6-14(16)22;1-2-3/h1-8H,21-24H2;3H,2H2,1H3/b17-11+,18-12+; |
| InchiKey | CFQULUVMLGZVAF-OYJDLGDISA-N |
| 分子式 Formula | C20H22N6OS2 |
| 分子量 Molecular Weight | 426.56 |
| 性状 | White to off-white solid powder |
| 储藏条件 Storage conditions | Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years). |
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