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Pactimibe free base
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:189198-30-9
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

Pactimibe is a ACAT inhibitor. Pactimibe stabilizes atherosclerotic plaque through macrophage acyl-cholesterol acyltransferase inhibition in WHHL rabbits. Pactimibe sulfate reduces and stabilizes atherosclerotic lesions by cholesterol-lowering and direct effects in apolipoprotein E-deficient mice. References: Kotsuma M, Tokui T, Freudenthaler S, Nishimura K. Effect of CYP2D6 polymorphism on pharmacokinetics of a novel ACAT inhibitor, pactimibe and its unique metabolite, R-125528. Int J Clin Pharmacol Ther. 2008 Nov;46(11):545-55. PubMed PMID: 19000552.

纯度:≥98%

CAS:189198-30-9