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PACMA 31
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PACMA 31图片
CAS NO:1401089-31-3
规格:≥98%
包装与价格:
包装价格(元)
25mg电议
50mg电议
100mg电议
250mg电议

产品介绍

PACMA 31 (PACMA31; PACMA-31) is a novel, orally bioavailable, and covalent/irreversible inhibitor of protein disulfide isomerase (PDI) with potentian anticancer activity. It acts by forming a covalent bond with the cysteine residue in the active site of PDI and inhibits PDI with an IC50 of 10 μM. PDI is an endoplasmic reticulum protein that regulates oxidative protein folding by catalyzing the breakage and reformation of disulfide bonds. PDI has been found to be upregulated in various cancers such as ovarian cancers.

纯度:≥98%

CAS:1401089-31-3