CAS NO: | 113457-06-0 |
包装: | 50mg, 100mg, 250mg |
规格: | ≥98% |
PD 121373 is a Benzothiopyrano-indazole cpd. The benzothiopyranoindazoles are potent inhibitors of nucleic acid synthesis, reducing both DNA and RNA synthesis to the same extent at similar concentrations. Like other known intercalators, these compounds produced DNA single- and double-strand breaks in a time- and concentration-dependent manner in L1210 cells. References: Fry DW, Besserer JA. Biochemical pharmacology and DNA-drug interactions by Cl-958, a new antitumor intercalator derived from a series of substituted 2H-[1]benzothiopyrano[4,3,2-cd]indazoles. Mol Pharmacol. 1988 Jan;33(1):84-92. PubMed PMID: 2447481.
纯度:≥98%
CAS:113457-06-0