Anguizole is a potent NS4B-AH2 inhibitor. Anguizole disrupts all of NS4B-AH2-mediated biological functions of NS4B. hronic hepatitis C virus (HCV) infection is responsible for severe liver diseases including liver cirrhosis and hepatocellular carcinoma. An HCV non-structural protein 4B (NS4B) plays an essential role in viral RNA genome replication by building multi-vesicular structures around endoplasmic reticulum membranes. References: Choi M, Lee S, Choi T, Lee C. A hepatitis C virus NS4B inhibitor suppresses viral genome replication by disrupting NS4B's dimerization/multimerization as well as its interaction with NS5A. Virus Genes. 2013 Dec;47(3):395-407. doi: 10.1007/s11262-013-0956-5. Epub 2013 Jul 19. PubMed PMID: 23868571.

纯度：≥98%

CAS：442666-98-0