Description: Cyclocytidine (also known as Ancitabine, and NSC 145668) is the prodrug of cytarabine, which is a pyrimidine nucleoside analog that inhibits the DNA synthesis and used mainly in the treatment of leukemia. Cyclocytidine is structurally similar to human deoxycytidine and can be incorporated into human DNA and then kills the cell. Cyclocytidine most affects rapidly dividing cells, which require DNA replication for mitosis. Cyclocytidine also inhibits both DNA and RNA polymerases and nucleotide reductase enzymes needed for DNA synthesis.

References: J Pharm Sci. 1984 Jul;73(7):896-902; Biochem Pharmacol. 1972 Feb 15;21(4):465-75.

Related CAS: 31698-14-3 (free base); 10212-25-6 (HCl)

纯度：≥98%

CAS：31698-14-3