Amtolmetin guacil, also known ST-679 and MED-15, is a non-acidic prodrug of tolmetin, having similar NSAID properties like tolmetin with additional analgesic, antipyretic, and gastro protective properties. Amtolmetin is formed by amidation of tolmetin by glycine. Amtolmetin guacil stimulates capsaicin receptors present on gastro intestinal walls, because of presence of vanillic moiety and also releases NO which is gastro protective. It also inhibits prostaglandin synthesis and cyclooxygenase (COX). References: Lin HC, Chen CJ, Chiang KH, Yen TY, Ho CM, Hwang KP, Su BH, Lin HC, Li TC, Lu JJ. Clonal dissemination of invasive and colonizing clonal complex 1 of serotype VI group B Streptococcus in central Taiwan. J Microbiol Immunol Infect. 2016 Dec;49(6):902-909. doi: 10.1016/j.jmii.2014.11.002. Epub 2014 Nov 11. PubMed PMID: 25560254.

纯度：≥98%

CAS：87344-06-7