PF-00489791, formerly known as PF-4634817, is an inhibitor of phosphodiesterase type 5. PF-00489791 will enhance the relaxation of blood vessels within the kidney and so reduce blood pressure, improving renal function. References: Scheele W, Diamond S, Gale J, Clerin V, Tamimi N, Le V, Walley R, Grover-Páez F, Perros-Huguet C, Rolph T, El Nahas M. Phosphodiesterase Type 5 Inhibition Reduces Albuminuria in Subjects with Overt Diabetic Nephropathy. J Am Soc Nephrol. 2016 Apr 25. pii: ASN.2015050473. [Epub ahead of print] PubMed PMID: 27113485.

纯度：≥98%

CAS：853003-48-2