PF-06465603 is a metabolite of PF-04691502 (InvivoChem CAT#: 202226), a highly potent and selective ATP competitive kinase inhibitor of class 1 PI3Ks and mTOR. References: Cheng H, Hoffman JE, Le PT, Pairish M, Kania R, Farrell W, Bagrodia S, Yuan J, Sun S, Zhang E, Xiang C, Dalvie D, Rahavendran SV. Structure-based design, SAR analysis and antitumor activity of PI3K/mTOR dual inhibitors from 4-methylpyridopyrimidinone series. Bioorg Med Chem Lett. 2013 May 1;23(9):2787-92. doi: 10.1016/j.bmcl.2013.02.020. Epub 2013 Feb 13. PubMed PMID: 23506825.

纯度：≥98%

CAS：1431626-44-6