PF-514273 is a highly selective CB1 antagonist. The Ki for binding to CB1 and CB2 receptors is 1 nM and 10 mM, respectively. PF-514273 inhibits food intake and weight gain in rodents. References: Pina MM, Cunningham CL. Effects of the novel cannabinoid CB1 receptor antagonist PF 514273 on the acquisition and expression of ethanol conditioned place preference. Alcohol. 2014 Aug;48(5):427-31. doi: 10.1016/j.alcohol.2014.01.013. Epub 2014 May 21. PubMed PMID: 24954022; PubMed Central PMCID: PMC4188509.

纯度：≥98%

CAS：851728-60-4