SYM2081 is a potent and highly selective kainate receptor agonist, with an IC50 for inhibition of [3H]-kainate binding of 35 nM and almost 3,000- and 200-fold selectivity for kainate receptors over AMPA and NMDA receptors respectively. SYM2081 also selectively inhibits the cloned excitatory amino acid transporter EAAT2 at higher concentrations. References: Mollerud S, Kastrup JS, Pickering DS. A pharmacological profile of the high-affinity GluK5 kainate receptor. Eur J Pharmacol. 2016 Oct 5;788:315-20. doi: 10.1016/j.ejphar.2016.06.049. Epub 2016 Jun 29. PubMed PMID: 27373850.

纯度：≥98%

CAS：31137-74-3