Pivampicillin Hydrochloride is an orally bioavailable pivalate ester prodrug of ampicillin with antibacterial activity. Pivampicillin is hydrolyzed into its active form ampicillin by esterases. Ampicillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis. References: Alausa KO, Osoba AO, Sogbetun AO. Clinical trial of pivampicillin hydrochloride (alphacillin) in gonorrhoea. West Afr J Pharmacol Drug Res. 1976 Jun;3(1):31-7. PubMed PMID: 799402.

纯度：≥98%

CAS：26309-95-5