AM 114 is a proteasome inhibitor. It is an inhibitor of chymotrypsin-like activity of the 20S proteasome. Also, AM-114 exhibits anticancer activity, inhibits cell growth in human colon cancer HCT116 p53+/+ cells. References: Russcher M, Chaves I, Lech K, Koch BC, Nagtegaal JE, Dorsman KF, Jong A', Kayser M, van Faassen HM, Kema IP, van der Horst GT, Gaillard CA. An observational study on disturbed peripheral circadian rhythms in hemodialysis patients. Chronobiol Int. 2015;32(6):848-57. doi: 10.3109/07420528.2015.1048868. Epub 2015 Jun 23. PubMed PMID: 26101944.

纯度：≥98%

CAS：856849-35-9