Poloxin-2 is a potent Plk1 PBD inhibitor. It acts by inducing mitotic arrest and apoptosis in cultured human tumor cells at low micromolar concentrations. References: Scharow A, Knappe D, Reindl W, Hoffmann R, Berg T. Development of Bifunctional Inhibitors of Polo-Like Kinase 1 with Low-Nanomolar Activities Against the Polo-Box Domain. Chembiochem. 2016 Apr 15;17(8):759-67. doi: 10.1002/cbic.201500535. Epub 2015 Dec 4. PubMed PMID: 26634982.

纯度：≥98%

CAS：321695-37-8