UK-356,202 is a potent and selective urokinase-type plasminogen activator (Ki = 37 nM). Urokinase plasminogen activator (uPA, urokinase) is a trypsinlike serine protease and a therapeutical target for many cancer types, including breast, ovarian, and pancreatic cancer. uPA is a valuable oncology target. References: Bayliss MA, Venn RF, Edgington AM, Webster R, Walker DK. Determination of a potent urokinase-type plasminogen activator, UK-356,202, in plasma at pg/mL levels using column-switching HPLC and fluorescence detection. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Jan 15;877(3):121-6. doi: 10.1016/j.jchromb.2008.11.038. Epub 2008 Dec 3. PubMed PMID: 19119083.

纯度：≥98%

CAS：223671-94-1