Alilusem is a novel diuretic, it possesses beneficial properties for the clinical treatment of hypertension. Characterization of the uptake mechanism for a novel loop diuretic, M17055, in Caco-2 cells, OATP-B plays a major role in the uptake of the novel loop diuretic M17055 from apical membranes in Caco-2 cells. References: Nishimura T, Kubo Y, Kato Y, Sai Y, Ogihara T, Tsuji A. Characterization of the uptake mechanism for a novel loop diuretic, M17055, in Caco-2 cells: involvement of organic anion transporting polypeptide (OATP)-B. Pharm Res. 2007 Jan;24(1):90-8. Epub 2006 Nov 14. PubMed PMID: 17103337.

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CAS：114417-20-8