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PSNCBAM-1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:877202-74-9
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
50mg电议
500mg电议

产品介绍

PSNCBAM-1 is a CB1 receptor negative allosteric modulator (IC50 are 45 and 209 nM) with hypophagic effects in vivo. PSNCBAM-1 allosteric antagonism may provide viable therapeutic alternatives to orthosteric CB(1) antagonists/inverse agonists in the treatment of CNS disease. References: Wang X, Horswill JG, Whalley BJ, Stephens GJ. Effects of the allosteric antagonist 1-(4-chlorophenyl)-3-[3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl]urea (PSNCBAM-1) on CB1 receptor modulation in the cerebellum. Mol Pharmacol. 2011 Apr;79(4):758-67. doi: 10.1124/mol.110.068197. PubMed PMID: 21189269.

纯度:≥98%

CAS:877202-74-9