Galiellalactone is a natural STAT3 inhibitor. It has been shown to inhibit IL-6-dependent JAK/STAT signaling and induce cell-cycle arrest in G2/M phase and apoptosis in androgen-insensitive prostate cancer cells via activation of ATM/ATR pathway. References: Schreiber D, Marx L, Felix S, Clasohm J, Weyland M, Schafer M, Klotz M, Lilischkis R, Erkel G, Schafer KH. Anti-inflammatory Effects of Fungal Metabolites in Mouse Intestine as Revealed by In vitro Models. Front Physiol. 2017 Aug 7;8:566. doi: 10.3389/fphys.2017.00566. eCollection 2017. PubMed PMID: 28824460; PubMed Central PMCID: PMC5545603.

纯度：≥98%

CAS：133613-71-5