VPC03090 is a Sphingosine-1-Phosphate Receptor Inhibitor. VPC03090 is an analogue of FTY-720, acts as antagonist for S1PR1 and S1PR3. VPC03090-P, converted from VPC03090 through the phosphorylation by SK-2, causes a reduction in tumor growth in mice with mammary cancer, and its orally bioavailable bioavailability is determined to be 30 hours. References: Kennedy PC, Zhu R, Huang T, Tomsig JL, Mathews TP, David M, Peyruchaud O, Macdonald TL, Lynch KR. Characterization of a sphingosine 1-phosphate receptor antagonist prodrug. J Pharmacol Exp Ther. 2011 Sep;338(3):879-89. doi: 10.1124/jpet.111.181552. PubMed PMID: 21632869; PubMed Central PMCID: PMC3164350.

纯度：≥98%

CAS：1392202-91-3