Pitstop 1, Novel clathrin inhibitor是一种有效的、选择性的网格蛋白非依赖性内吞作用抑制剂,IC50 为 18 uM(抑制网格蛋白 TD-amphiphysin B/C 复合物的形成); 抑制神经元和原位突触小泡的内吞循环。
中文别名 | 1332879-51-2;新型网格蛋白抑制剂 |
英文别名 | Pitstop 1;Novel clathrin inhibitor;Pitstop1 |
CAS号 | 1332879-51-2 |
SMILES | NC1=CC=C(CN2C(C3=CC(S(=O)(O[Na])=O)=CC4=C3C(C2=O)=CC=C4)=O)C=C1 |
Inchi | InChI=1S/C19H14N2O5S.Na/c20-13-6-4-11(5-7-13)10-21-18(22)15-3-1-2-12-8-14(27(24,25)26)9-16(17(12)15)19(21)23;/h1-9H,10,20H2,(H,24,25,26);/q;+1/p-1 |
InchiKey | MKPPGLKJTZAXNE-UHFFFAOYSA-M |
分子式 Formula | C19H13N2NaO5S |
分子量 Molecular Weight | 404.37 |
性状 | Solid powder |
储藏条件 Storage conditions | Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years). |