VU0366248 is a negative allosteric modulator of mGlu5. References: Identification of Specific Ligand–Receptor Interactions That Govern Binding and Cooperativity of Diverse Modulators to a Common Metabotropic Glutamate Receptor 5 Allosteric Site Karen J. Gregory, Elizabeth D. Nguyen, Chrysa Malosh, Jeffrey L. Mendenhall, Jessica Z. Zic, Brittney S. Bates, Meredith J. Noetzel, Emma F. Squire, Eric M. Turner, Jerri M. Rook, Kyle A. Emmitte, Shaun R. Stauffer, Craig W. Lindsley, Jens Meiler, P. Jeffrey Conn ACS Chem Neurosci. 2014 Apr 16; 5(4): 282–295. Published online 2014 Feb 16. doi: 10.1021/cn400225x PMCID: PMC3990945

纯度：≥98%

CAS：1243310-20-4