VU0255035 is a highly selective muscarinic M1 antagonist (Ki = 14.87 nM). VU0255035 targets the M1 orthosteric site with greater than 75-fold selectivity over the other receptor subtypes. References: Miller SL, Aroniadou-Anderjaska V, Pidoplichko VI, Figueiredo TH, Apland JP, Krishnan JK, Braga MF. The M1 Muscarinic Receptor Antagonist VU0255035 Delays the Development of Status Epilepticus after Organophosphate Exposure and Prevents Hyperexcitability in the Basolateral Amygdala. J Pharmacol Exp Ther. 2017 Jan;360(1):23-32. Epub 2016 Oct 31. PubMed PMID: 27799295; PubMed Central PMCID: PMC5193080.

纯度：≥98%

CAS：1135243-19-4