VU591 (VU-591) is a novel and potent ROMK (renal outer medullary potassium channel) inhibitor, or Kir1.1 inhibitor with diuretic effects. It inhibits ROMK with an IC50 of 0.24 μM. The renal outer medullary potassium (K+) channel, ROMK (Kir1.1), is a putative drug target for a novel class of loop diuretic that would lower blood volume and pressure without causing hypokalemia.

纯度：≥98%

CAS：1222810-74-3