VU0486846 is a highly selective M1 positive allosteric modulator (PAM). References: Bertron JL, Cho HP, Garcia-Barrantes PM, Panarese JD, Salovich JM, Nance KD, Engers DW, Rook JM, Blobaum AL, Niswender CM, Stauffer SR, Conn PJ, Lindsley CW. The discovery of VU0486846: steep SAR from a series of M(1) PAMs based on a novel benzomorpholine core. Bioorg Med Chem Lett. 2018 Jul 1;28(12):2175-2179. doi: 10.1016/j.bmcl.2018.05.009. Epub 2018 May 5. PubMed PMID: 29754948.

纯度：≥98%

CAS：1788055-11-7