Melafolone is a natural dual inhibitor of cox-2 and egfr, improving program death 1 (pd-1) checkpoint blockade therapy through normalizing tumor vasculature and pd-l1 downregulation References: Tang H, Liu Y, Wang C, Zheng H, Chen Y, Liu W, Chen X, Zhang J, Chen H, Yang Y, Yang J. Inhibition of COX-2 and EGFR by Melafolone Improves Anti-PD-1 Therapy through Vascular Normalization and PD-L1 Downregulation in Lung Cancer. J Pharmacol Exp Ther. 2019 Mar;368(3):401-413. doi: 10.1124/jpet.118.254359. Epub 2018 Dec 27. PubMed PMID: 30591531.

纯度：≥98%

CAS：129724-42-1