WB403 is a TGR5 activator. WB403 significantly improves glucose tolerance and decreases fasting blood glucose, postprandial blood glucose and HbA1c in type 2 diabetic mice. WB403 also increases pancreatic β-cells and restores the normal distribution pattern of α-cell and β-cell in islets. References: Zheng C, Zhou W, Wang T, You P, Zhao Y, Yang Y, Wang X, Luo J, Chen Y, Liu M, Chen H. A Novel TGR5 Activator WB403 Promotes GLP-1 Secretion and Preserves Pancreatic β-Cells in Type 2 Diabetic Mice. PLoS One. 2015 Jul 24;10(7):e0134051. doi: 10.1371/journal.pone.0134051. eCollection 2015. PubMed PMID: 26208278; PubMed Central PMCID: PMC4514850.

纯度：≥98%

CAS：1594041-84-5