X 14868A, formerly known as Maduramicin, is a natural polyether ionophore antibiotic first extracted from the actinomycete Actinomadura rubra. It is cytotoxic against Cryptosporidium spp. and is commonly used in veterinary medicine as an anti-coccidial agent. Maduramicin is also cytotoxic against Plasmodium gametocytes and potentiates the gametocytocidal activity of the pyrazoleamide PA21A050. References: Liu CM, Hermann TE, Downey A, Prosser BL, Schildknecht E, Palleroni NJ, Westley JW, Miller PA. Novel polyether antibiotics X-14868A, B, C, and D produced by a Nocardia. Discovery, fermentation, biological as well as ionophore properties and taxonomy of the producing culture. J Antibiot (Tokyo). 1983 Apr;36(4):343-50. PubMed PMID: 6853364.

纯度：≥98%

CAS：79356-08-4