Lascufloxacin, formerly known as KRP-AM-1977, is a potent antibacterial drug candidate. Lascufloxacin showed a broad spectrum of activity against various clinical isolates. Especially, lascufloxacin showed the most potent activity against gram-positive bacteria among the quinolones tested. Furthermore, lascufloxacin showed incomplete cross-resistance against existing quinolone-resistant strains. Enzymatic analysis indicated that lascufloxacin showed potent inhibitory activity against both wild-type and mutated target enzymes. Lascufloxacin may be useful in treating infections caused by various pathogens, including quinolone-resistant strains. References: Ohya K, Takano J, Manita S. In Vitro Mechanistic Study of the Distribution of Lascufloxacin into Epithelial Lining Fluid. Antimicrob Agents Chemother. 2019 Mar 27;63(4). pii: e02208-18. doi: 10.1128/AAC.02208-18. Print 2019 Apr. PubMed PMID: 30718243; PubMed Central PMCID: PMC6437485.

纯度：≥98%

CAS：848416-07-9