ZINC08383544 is a specific pyruvate kinase M2 activator which promotes the formation of PKM2 tetramer. ZINC08383544 effectively blocks PKM2 nuclear translocation, and inhibits the growth of tumor. References: Li Y, Bao M, Yang C, Chen J, Zhou S, Sun R, Wu C, Li X, Bao J. Computer-aided identification of a novel pyruvate kinase M2 activator compound. Cell Prolif. 2018 Dec;51(6):e12509. doi: 10.1111/cpr.12509. Epub 2018 Aug 21. PubMed PMID: 30133040.

纯度：≥98%

CAS：618361-63-0