您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Formestane(CGP-32349)
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Formestane(CGP-32349)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Formestane(CGP-32349)图片
CAS NO:566-48-3
规格:≥98%
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议
1g电议
2g电议
5g电议

产品介绍
Formestane (formerly also known as CGP-32349, NSC 282175) is a second generation, selective, orally bioactive and synthetic steroidal aromatase inhibitor with an IC50 of 80 nM. Formestane is a substance with anticancer activity. Formestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens.
理化性质和储存条件
Molecular Weight (MW)302.41
FormulaC19H26O3
CAS No.566-48-3
Storage-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)DMSO: 61 mg/mL (201.7 mM)
Water: <1 mg/mL
Ethanol:<1 mg/mL
Other info
Chemical Name: (8R,9S,10R,13S,14S)-4-hydroxy-10,13-dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17(2H,6H)-dione
InChi Key: OSVMTWJCGUFAOD-KZQROQTASA-N
InChi Code: InChI=1S/C19H26O3/c1-18-10-8-15(20)17(22)14(18)4-3-11-12-5-6-16(21)19(12,2)9-7-13(11)18/h11-13,22H,3-10H2,1-2H3/t11-,12-,13-,18+,19-/m0/s1
SMILES Code: O=C(C(O)=C1CC[C@@]2([H])[C@]3([H])CC4)CC[C@]1(C)[C@@]2([H])CC[C@]3(C)C4=O
SynonymsCGP-32349, NSC282175; NSC-282175; NSC 282175; CGP32349; CGP 32349; CGP-32349; 4OHA; 4OHAD; Formestane; Lentaron.