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Gastrin-Releasing Peptide,human
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Gastrin-Releasing Peptide,human图片
CAS NO:93755-85-2
规格:≥98%
包装与价格:
包装价格(元)
1mg电议
2mg电议
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍

Gastrin-Releasing Peptide, human (GRP) is a peptide belonging to the mammalian homolog of bombesin (BBS) class, it functions as a mitogen for multiple cancers, such as neuroblastoma. GRP is a ligand for GRPR (GRP receptor) and is expressed in a subtype of peptidergic dorsal root ganglion neurons. It is not a classical hypothalamic-hypophyseal regulatory hormone since it plays only a perfunctory role in the mediation of pituitary hormone release. GRP functions as an autocrine growth factor for nueroblastoma. It facilitates cell survival in PI3K/AKT (phosphatidylinositol-3-kinase/ v-Akt murine thymoma viral oncogene)-mediated manner and cell proliferation and angiogenesis in neuroblastoma. This peptide is involved in the release of gastrin and the control of gastric acid secretion and motor function. In patients with atopic dermatitis, the serum levels of this peptide are linked with pruritus

纯度:≥98%

CAS:93755-85-2