DUBs-IN-3 is a potent deubiquitinase (USP) enzyme inhibitor found in reference compound 22c with an IC50 of 0.56 μM for USP8. References: Colombo M, et al. Synthesis and biological evaluation of 9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile analogues as potential inhibitors of deubiquitinating enzymes. ChemMedChem. 2010 Apr 6;5(4):552-8.

纯度：≥98%

CAS：924296-17-3