Mitiglinide Calcium(KAD-1229)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO: | 145525-41-3 |
规格: | ≥98% |
包装与价格:
包装 | 价格(元) |
50mg | 电议 |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
1g | 电议 |
5g | 电议 |
10g | 电议 |
产品介绍
理化性质和储存条件
Molecular Weight (MW) | 668.88 |
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Formula | (C19H24NO3)2.Ca |
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CAS No. | 145525-41-3 (Mitiglinide Calcium) |
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Storage | -20℃ for 3 years in powder form |
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-80℃ for 2 years in solvent |
Solubility (In vitro) | DMSO: <1 mg/mL |
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Water:<1 mg/mL |
Ethanol: 2 mg/mL (2.99 mM) |
SMILES Code | O=C([O-])C(CC1=CC=CC=C1)CC(N2C[C@]3([H])CCCC[C@]3([H])C2)=O.O=C([O-])C(CC4=CC=CC=C4)
CC(N5C[C@]6([H])CCCC[C@]6([H])C5)=O.[Ca+2] |
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Synonyms | KAD-1229; S 21403; KAD 1229; S21403; KAD1229; S-21403; Mitiglinide calcium; Glufast. |
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实验参考方法
In Vitro | In vitro activity: Mitiglinide (KAD-1229; S21403) is a drug for the treatment of type 2 diabetes; it is a highly selective KATP channel antagonist. IC50 value: Target: KATP channel Mitiglinide is a hypoglycemic agent that closes adenosine triphosphate (ATP)-sensitive potassium channels (KATP channel s) in the pancreatic β-islet cells. Mitiglinide stimulates insulin secretion by stimulating Ca2+ influx. |
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In Vivo |
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Animal model |
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Formulation & Dosage |
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References |
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