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Mitiglinide Calcium(KAD-1229)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Mitiglinide Calcium(KAD-1229)图片
CAS NO:145525-41-3
规格:≥98%
包装与价格:
包装价格(元)
50mg电议
100mg电议
250mg电议
500mg电议
1g电议
5g电议
10g电议

产品介绍
理化性质和储存条件
Molecular Weight (MW)668.88
Formula(C19H24NO3)2.Ca
CAS No.145525-41-3 (Mitiglinide Calcium)
Storage-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)DMSO: <1 mg/mL
Water:<1 mg/mL
Ethanol: 2 mg/mL (2.99 mM)
SMILES Code O=C([O-])C(CC1=CC=CC=C1)CC(N2C[C@]3([H])CCCC[C@]3([H])C2)=O.O=C([O-])C(CC4=CC=CC=C4)


CC(N5C[C@]6([H])CCCC[C@]6([H])C5)=O.[Ca+2]

SynonymsKAD-1229; S 21403; KAD 1229; S21403; KAD1229; S-21403; Mitiglinide calcium; Glufast.
实验参考方法
In Vitro

In vitro activity: Mitiglinide (KAD-1229; S21403) is a drug for the treatment of type 2 diabetes; it is a highly selective KATP channel antagonist. IC50 value: Target: KATP channel Mitiglinide is a hypoglycemic agent that closes adenosine triphosphate (ATP)-sensitive potassium channels (KATP channel s) in the pancreatic β-islet cells. Mitiglinide stimulates insulin secretion by stimulating Ca2+ influx.

In Vivo
Animal model
Formulation & Dosage
References