ABT-100 (ABT100) is a novel and potent farnesyltransferase inhibitor with a broad-spectrum antitumor activity. ABT-100 inhibits cancer cell proliferation with IC50s of 2.2 nM, 3.8 nM, 5.9 nM, 6.9 nM, 9.2 nM, 70 nM and 818 nM for EJ-1, DLD-1, MDA-MB-231, HCT-116, MiaPaCa-2, PC-3, and DU-145 cells, respectively.. It also increases apoptosis and decreases angiogenesis

纯度：≥98%

CAS：450839-40-4