Omadacycline (PTK 0796) mesylate，(PTK0796甲磺酸盐, PTK 0796 mesylate; Amadacycline mesylate)首创的具有口服活性的氨基甲基环素抗菌剂，是一种四环素类抗生素。Omadacycline mesylate 通过与 30S 核糖体亚基结合来抑制细菌蛋白质的合成。Omadacycline mesylate 对多种细菌表现出活性，包括好氧和厌氧革兰氏阳性细菌和革兰氏阴性细菌，非典型病原体。Omadacycline mesylate 可用于研究急性细菌性皮肤和皮肤结构感染，感染性肺炎和尿路感染。
| 中文别名 | Omadacycline mesylate(cas:1196800-40-4),甲磺酸盐,甲磺酸环丙环素,PTK0796甲磺酸盐,甲磺酸金刚霉素,阿马达环素甲磺酸盐,阿马达环素（甲磺酸盐),PTK0796甲磺酸盐,Amadacycline甲磺酸盐, |
| 英文别名 | Omadacycline mesylate,Omadacycline,Omadacycline mesylate,Amadacycline methanesulfonate,Amadacycline (methanesulfonate), |
| CAS号 | 1196800-40-4 |
| SMILES | CS(=O)(O)=O.O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@]3([H])CC4=C(C(C3=C(O)[C@@]21O)=O)C(O)=C(CNCC(C)(C)C)C=C4N(C)C)N |
| Inchi | InChI=1S/C29H40N4O7.CH4O3S/c1-28(2,3)12-31-11-14-10-17(32(4)5)15-8-13-9-16-21(33(6)7)24(36)20(27(30)39)26(38)29(16,40)25(37)18(13)23(35)19(15)22(14)34;1-5(2,3)4/h10,13,16,21,31,34,36-37,40H,8-9,11-12H2,1-7H3,(H2,30,39);1H3,(H,2,3,4)/t13-,16-,21-,29-;/m0./s1 |
| InchiKey | KBKDNTRIPNHHND-XGLFQKEBSA-N |
| 分子式 Formula | C30H44N4O10S |
| 分子量 Molecular Weight | 652.76 |
| 性状 | Solid |
| 储藏条件 Storage conditions | 4℃, protect from light * In solvent : -80℃, 6 months月; -20℃, 1 month月 (protect from light) |
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