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ORM-10962
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:763926-98-3
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

ORM-10962 is a potent, highly selective sodium-calcium exchanger (NCX) inhibitor, with IC50 of 67 and 55 nM for the reverse and forward mode inhibition, respectively. References: Kohajda Z, et al. The Effect of a Novel Highly Selective Inhibitor of the Sodium/Calcium Exchanger (NCX) on Cardiac Arrhythmias in In Vitro and In Vivo Experiments. PLoS One. 2016 Nov 10;11(11):e0166041. [2]. Oravecz K, et al. Inotropic effect of NCX inhibition depends on the relative activity of the reverse NCX assessed by a novel inhibitor ORM-10962 on canine ventricular myocytes. Eur J Pharmacol. 2018 Jan 5;818:278-286.

纯度:≥98%

CAS:763926-98-3