生物活性
QX 314 chloride是利多卡因的膜不可渗透的季衍生物,一种电压激活的Na+通道阻滞剂。
化学数据
目录号 | A13760 |
作用机制 | Blocker (阻断剂) |
M. Wt | 298.85 |
Formula | C16H27N2OCl |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
CAS No. | CAS: 5369-03-9 |
Synonyms | QX-314,QX314, N-Ethyllidocaine chloride |
SMILES | CC[N+](CC)(CC)CC(=O)NC1=C(C=CC=C1C)C.[Cl-] |
储备液配制
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
0.1 mM | 33.46 mL | 167.31 mL | 334.62 mL |
0.5 mM | 6.69 mL | 33.46 mL | 66.92 mL |
1 mM | 3.35 mL | 16.73 mL | 33.46 mL |
5 mM | 0.67 mL | 3.35 mL | 6.69 mL |
*The above data is based on the productmolecular weight 298.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.