21-deacetyldeflazacort is a major and 21-deacetylated metabolite of deflazacort, which is a prednisolone analog and systemic corticosteroid approved for the treatment of rheumatoid arthritis (RA) and lupus. Deflazacort (DL-458-IT; L-5458; ML-458;
ML458; Cortax; Decortil; Deflanil; Flezacor; trade
name: Emflaza) is a potent glucocorticoid drug used as an
anti-inflammatory and immunosuppressant.