Shz-1 is a novel activator of early cardiac genes (including Nkx2.5) in pluripotent stem cells. Shz-1 activates the axolotl TPM4 promoter-driven ectopic expression in C2C12 cells and the promoters of a variety of genes including axolotl TPM4. References: Nan C, Dube S, Matoq A, Mikesell L, Abbott L, Alshiekh-Nasany R, Chionuma H, Huang X, Poiesz BJ, Dube DK. Expression of sarcomeric tropomyosin in striated muscles in axolotl treated with shz-1, a small cardiogenic molecule. Cardiovasc Toxicol. 2015 Jan;15(1):29-40. doi: 10.1007/s12012-014-9265-z. PubMed PMID: 24958154.

纯度：≥98%

CAS：326886-05-9