Falcarindiol is a natural polyyne found in many food and dietary plants, with antifungal activity. Falcarindiol has a strong and specific anticancer effect in breast cancer cells. Falcarindiol promotes cholesterol efflux from THP-1 macrophages by increasing ABCA1 gene transcription and protein stability. References: B.Garrod, et al. Cis-heptadeca-1,9-diene-4,6-diyne-3,8-diol, an antifungal polyacetylene from carrot root tissue. Physiological Plant Pathology. 1978 Sep;13(2):41-246. [2]. Lu T, et al. Autophagy contributes to falcarindiol-induced cell death in breast cancer cells with enhanced endoplasmic reticulum stress. PLoS One. 2017 Apr 25;12(4):e0176348. [3]. Wang L, et al. The Dietary Constituent Falcarindiol Promotes Cholesterol Efflux from THP-1 Macrophages by Increasing ABCA1 Gene Transcription and Protein Stability. Front Pharmacol. 2017 Sep 1;8:596.

纯度：≥98%

CAS：55297-87-5