SB236057 is a potent and selective inverse agonist for the serotonin receptor 5-HT, acting especially at 5-HT autoreceptors on nerve terminals. It produces a rapid increase in serotonin levels in the brain, and was originally researched as a potential antidepressant. SB-236,057 also acts as a potent teratogen, producing severe musculoskeletal birth defects when rodents were exposed to it during pregnancy. References:

纯度：≥98%

CAS：180083-49-2