Nivalenol, a naturally occuring mycotoxin of the trichothecene class, is classified as type B trichotecenes toxins produced by Fusarium graminearum, and is a fungal metabolite present in agricultural product. Nivalenol induces cell death through caspase-dependent mechanisms and via the intrinsic apoptotic pathway. Nivalenol affects the immune system, causes emesis, growth retardation, reproductive disorders and has a haematotoxic/myelotoxic effect.